Global pharma: Surviving the patent cliff challenge
Global pharma players are facing the risk of a patent cliff, where the loss in sales for the original drugmaker can be huge, as illustrated in the case of Roche’s drug Avastin.
DBS iWealth6 Jul 2024
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Global pharmaceutical industry overview::

  • Many major pharmaceutical companies are facing the risk of a "patent cliff".
  • When patents expire, generic versions of drugs enter the market at lower prices, impacting original drug sales.
  • Taken to example case of Roche's drug Avastin saw a 75% sales drop from USD 7.1bn in 2019 to USD 1.8bn in 2023 after its patent expired.

Financial Impact and Predictions:

  • IQVIA1 predicts a significant increase in sales loss due to patent expiry, from USD 67bn (2018-23) to USD 145bn (2024-28) in the US alone.
  • Eight out of 13 major pharmaceutical players could see 30% or more of their sales exposed to patent expiry in the US by 2026, leading to uncertainty in their sales forecasts.

 

1 American multinational company serving the combined industries of health information technology and clinical research.

 

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However there are certain company faces low risk of patent expiry and visible catalysts ahead.

Company with low patent cliff risk:

  • One pharmaceutical company stands out with less than 20% of its sales exposed to patent cliffs.
  • This company has potential share price catalysts in the next 12 months, including five new drugs in its pipeline awaiting approval or new clinical data readouts.
  • Potential upcoming treatments include those for diabetes, Alzheimer’s disease, atopic dermatitis, and atherosclerotic cardiovascular disease.

Below are some Equity Funds with exposure to healthcare and pharmaceutical sectors*

  • Schroder Global Sharia Equity Fund
  • BNP Paribas Cakra Syariah USD
  • Bahana Global Healthcare Sharia USD
  • Manulife Saham Syariah Golden Asia USD
  • Batavia Global ESG Sharia Equity USD
*based on portfolio holding in fund fact sheet as per May 2024


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PT Bank DBS Indonesia (“DBSI”) is licensed and supervised by the Indonesia Financial Services Authority (OJK) and a member of the Indonesia Deposit Insurance Corporation (LPS). This publication is not and does not constitute or form part of any offer, recommendation, invitation or solicitation to you to subscribe to or to enter into any transaction as described, nor is it calculated to invite or permit the making of offers to the public to subscribe to or enter into any transaction for cash or other consideration and should not be viewed as such.